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In general, over the counter antihistamines are as effective as prescription antihistamines. However, the over the counter varieties usually cause more sedation. A good rule of thumb is to take the over the counter antihistamines only when you will not have to drive or perform any tasks requiring alertness. Most people find that the prescription varieties cause less sedation and opt for those when they need to be taken on a regular basis.
|Jennifer Mathes, Ph.D.|